LC-MS Sample Preparation

From Raw Sample to LC-MS Injection — True “Sample In, Result Out” Automation

LC-MS is a cornerstone of modern analytical science, yet upstream sample preparation remains labor-intensive and prone to errors. Biolinkron’s automated SPE system provides an integrated solution covering purification and final concentration, transforming complex manual workflows into seamless, reproducible automation.

Key Benefits:

✅ End-to-End Automation with Modular Flexibility

  • Automates major steps: purification
  • Can function as a stand-alone module or within fully connected workflows such as integrating upstream digestion

✅ Precise, MS-Compatible Output

  • Tight control over sample volume and concentration for consistent injection
  • Removes salts, surfactants, and other interfering compounds to reduce ion suppression
  • Delivered in 96-well plates ready for LC-MS analysis

✅ Built for Lab Integration & Compliance

  • Open API supports LIMS and lab orchestration systems
  • Compatible with robotic platforms (Opentrons, Hamilton, Tecan, etc.)

Common Use Cases:

  • Multi-omics workflows (e.g., proteo-metabolomics)
  • Pre-injection sample prep for LC-MS pipelines

Recommended Models:

Model Features Ideal For
Biolinkron S96 Full-stack automation, high throughput Core labs, large-cohort projects, service facilities
Biolinkron S8 Modular, customizable workflows R&D, method development, pilot-scale experiments